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CD247 Mouse mAb

63312

CD247 Mouse mAb

CD247 Mouse mAb (catalogue number 63312) is a mouse-derived primary antibody validated for Immunohistochemistry, Immunofluorescence, Flow cytometry, reactive with Human samples. It targets T-cell surface glycoprotein CD3 zeta chain (CD247): Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Immunohistochemistry Immunofluorescence Flow cytometry
UniProt ID
P20963
Gene
CD247
Target organism
Homo sapiens
Catalogue number
63312
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: T-cell surface glycoprotein CD3 zeta chain (CD247) · Homo sapiens

Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.

Subcellular location: Cell membrane

Tissue specificity: Expressed in normal lymphoid tissue and in peripheral blood mononuclear cells (PBMCs)

Sequence length: 164 aa · 18696 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.