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BIN1 Mouse mAb

63150

BIN1 Mouse mAb

BIN1 Mouse mAb (catalogue number 63150) is a mouse-derived primary antibody validated for Western blot, Immunohistochemistry, Flow cytometry, reactive with Human, Mouse samples. It targets Myc box-dependent-interacting protein 1 (BIN1): Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human, Mouse
Applications
Western blot Immunohistochemistry Flow cytometry
UniProt ID
O00499
Gene
BIN1
Target organism
Homo sapiens
Catalogue number
63150
Brand
LABO Scientific
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Target background

Target: Myc box-dependent-interacting protein 1 (BIN1) · Homo sapiens

Is a key player in the control of plasma membrane curvature, membrane shaping and membrane remodeling. Required in muscle cells for the formation of T-tubules, tubular invaginations of the plasma membrane that function in depolarization-contraction coupling. Is a negative regulator of endocytosis. Is also involved in the regulation of intracellular vesicles sorting, modulation of BACE1 trafficking and the control of amyloid-beta production. In neuronal circuits, endocytosis regulation may influence the internalization of PHF-tau aggregates.

Subcellular location: Nucleus; Cytoplasm; Endosome; Cell membrane, sarcolemma, T-tubule

Tissue specificity: Ubiquitous. Highest expression in the brain and muscle. Expressed in oligodendrocytes. Isoform IIA is expressed only in the brain, where it is detected in the gray matter, but not in the white matter. Isoform BIN1 is widely expressed with highest expression in skeletal muscle

Sequence length: 593 aa · 64699 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.