Loading...
SAK Antibody

62068

SAK Antibody

SAK Antibody (catalogue number 62068) is a rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets Serine/threonine-protein kinase PLK4 (PLK4): Serine/threonine-protein kinase that plays a central role in centriole duplication. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
O00444
Gene
PLK4
Target organism
Homo sapiens
Catalogue number
62068
Brand
LABO Scientific
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.

Target background

Target: Serine/threonine-protein kinase PLK4 (PLK4) · Homo sapiens

Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CPAP, CCP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Phosphorylates 'Ser-151' of FBXW5 during the G1/S transition, leading to inhibit FBXW5 ability to ubiquitinate SASS6.

Subcellular location: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole; Nucleus, nucleolus; Cleavage furrow; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Sequence length: 970 aa · 108972 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.