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Legumain Rabbit mAb

59991

Legumain Rabbit mAb

Legumain Rabbit mAb (catalogue number 59991) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for Western blot, reactive with Human Mouse Rat samples. It targets Legumain (LGMN): Has a strict specificity for hydrolysis of asparaginyl bonds. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
Western blot
UniProt ID
Q99538
Gene
LGMN
Target organism
Homo sapiens
Catalogue number
59991
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: Legumain (LGMN) · Homo sapiens

Has a strict specificity for hydrolysis of asparaginyl bonds. Can also cleave aspartyl bonds slowly, especially under acidic conditions. Involved in the processing of proteins for MHC class II antigen presentation in the lysosomal/endosomal system. Also involved in MHC class I antigen presentation in cross-presenting dendritic cells by mediating cleavage and maturation of Perforin-2 (MPEG1), thereby promoting antigen translocation in the cytosol. Required for normal lysosomal protein degradation in renal proximal tubules. Required for normal degradation of internalized EGFR.

Subcellular location: Lysosome

Tissue specificity: Ubiquitous. Particularly abundant in kidney, heart and placenta

Sequence length: 433 aa · 49411 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.