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DIAPH1 Rabbit mAb

59887

DIAPH1 Rabbit mAb

DIAPH1 Rabbit mAb (catalogue number 59887) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB IHC ICC/IF, reactive with Human Mouse Rat samples. It targets Protein diaphanous homolog 1 (DIAPH1): Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IHC ICC/IF
UniProt ID
O60610
Gene
DIAPH1
Target organism
Homo sapiens
Catalogue number
59887
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: Protein diaphanous homolog 1 (DIAPH1) · Homo sapiens

Actin nucleation and elongation factor required for the assembly of F-actin structures, such as actin cables and stress fibers. Binds to the barbed end of the actin filament and slows down actin polymerization and depolymerization. Required for cytokinesis, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics. Functions as a scaffold protein for MAPRE1 and APC to stabilize microtubules and promote cell migration. Has neurite outgrowth promoting activity.

Subcellular location: Cell membrane; Cell projection, ruffle membrane; Cytoplasm, cytoskeleton; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle; Cytoplasm; Nucleus

Tissue specificity: Expressed in brain, heart, placenta, lung, kidney, pancreas, liver, skeletal muscle and cochlea. Expressed in platelets

Sequence length: 1272 aa · 141347 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.