Loading...
GEF H1 Rabbit mAb

59765

GEF H1 Rabbit mAb

GEF H1 Rabbit mAb (catalogue number 59765) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB ICC/IF FC, reactive with Human Mouse Rat samples. It targets Rho guanine nucleotide exchange factor 2 (ARHGEF2): Activates Rho-GTPases by promoting the exchange of GDP for GTP. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB ICC/IF FC
UniProt ID
Q92974
Gene
ARHGEF2
Target organism
Homo sapiens
Catalogue number
59765
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: Rho guanine nucleotide exchange factor 2 (ARHGEF2) · Homo sapiens

Activates Rho-GTPases by promoting the exchange of GDP for GTP. May be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Binds Rac-GTPases, but does not seem to promote nucleotide exchange activity toward Rac-GTPases, which was uniquely reported in PubMed:9857026. May stimulate instead the cortical activity of Rac. Inactive toward CDC42, TC10, or Ras-GTPases.

Subcellular location: Cytoplasm, cytoskeleton; Cytoplasm; Cell junction, tight junction; Golgi apparatus; Cytoplasm, cytoskeleton, spindle; Cell projection, ruffle membrane; Cytoplasmic vesicle

Sequence length: 986 aa · 111543 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.