Loading...
MMP2 Rabbit mAb

59608

MMP2 Rabbit mAb

MMP2 Rabbit mAb (catalogue number 59608) is a recombinant rabbit-derived primary antibody validated for WB ICC/IF FC, reactive with Human Mouse Rat samples. It targets 72 kDa type IV collagenase (MMP2): Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB ICC/IF FC
UniProt ID
P08253
Gene
MMP2
Target organism
Homo sapiens
Catalogue number
59608
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: 72 kDa type IV collagenase (MMP2) · Homo sapiens

Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro.

Subcellular location: Secreted, extracellular space, extracellular matrix; Membrane; Nucleus

Tissue specificity: Produced by normal skin fibroblasts. PEX is expressed in a number of tumors including gliomas, breast and prostate

Sequence length: 660 aa · 73882 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.