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PDK1 Rabbit mAb

59476

PDK1 Rabbit mAb

PDK1 Rabbit mAb (catalogue number 59476) is a recombinant rabbit-derived primary antibody validated for WB IP, reactive with Human Mouse Rat samples. It targets [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1): Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IP
UniProt ID
Q15118
Gene
PDK1
Target organism
Homo sapiens
Catalogue number
59476
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (PDK1) · Homo sapiens

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia

Subcellular location: Mitochondrion matrix

Tissue specificity: Expressed predominantly in the heart. Detected at lower levels in liver, skeletal muscle and pancreas

Sequence length: 436 aa · 49244 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.