59346
Podoplanin Rabbit mAb
Podoplanin Rabbit mAb (catalogue number 59346) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human Mouse Rat samples. It targets Podoplanin (PDPN): Mediates effects on cell migration and adhesion through its different partners. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Applications
- Western blot
- UniProt ID
- Q86YL7
- Gene
- PDPN
- Target organism
- Homo sapiens
- Catalogue number
- 59346
- Brand
- LABO Scientific
- Storage
- Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Target background
Target: Podoplanin (PDPN) · Homo sapiens
Mediates effects on cell migration and adhesion through its different partners. During development plays a role in blood and lymphatic vessels separation by binding CLEC1B, triggering CLEC1B activation in platelets and leading to platelet activation and/or aggregation. Interaction with CD9, on the contrary, attenuates platelet aggregation induced by PDPN. Through MSN or EZR interaction promotes epithelial-mesenchymal transition (EMT) leading to ERZ phosphorylation and triggering RHOA activation leading to cell migration increase and invasiveness.
Subcellular location: Membrane; Cell projection, lamellipodium membrane; Cell projection, filopodium membrane; Cell projection, microvillus membrane; Cell projection, ruffle membrane; Membrane raft; Apical cell membrane; B
Tissue specificity: Highly expressed in placenta, lung, skeletal muscle and brain. Weakly expressed in brain, kidney and liver. In placenta, expressed on the apical plasma membrane of endothelium. In lung, expressed in alveolar epithelium.
Sequence length: 162 aa · 16698 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il