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HMGCR Rabbit mAb

59257

HMGCR Rabbit mAb

HMGCR Rabbit mAb (catalogue number 59257) is a recombinant rabbit-derived primary antibody validated for WB IP, reactive with Human Mouse Rat samples. It targets 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR): Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IP
UniProt ID
P04035
Gene
HMGCR
Target organism
Homo sapiens
Catalogue number
59257
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) · Homo sapiens

Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs

Subcellular location: Endoplasmic reticulum membrane; Peroxisome membrane

Tissue specificity: Ubiquitously expressed with the highest levels in the cerebellum, fetal brain, testis, skin and adrenal gland

Sequence length: 888 aa · 97476 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.