Loading...
Raf1 Rabbit mAb

59173

Raf1 Rabbit mAb

Raf1 Rabbit mAb (catalogue number 59173) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB ICC/IF, reactive with Human samples. It targets RAF proto-oncogene serine/threonine-protein kinase (RAF1): Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiati… Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human
Applications
WB ICC/IF
UniProt ID
P04049
Gene
RAF1
Target organism
Homo sapiens
Catalogue number
59173
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: RAF proto-oncogene serine/threonine-protein kinase (RAF1) · Homo sapiens

Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal-regulated kinases (MAPK3/ERK1 and MAPK1/ERK2).

Subcellular location: Cytoplasm; Cell membrane; Mitochondrion; Nucleus

Tissue specificity: In skeletal muscle, isoform 1 is more abundant than isoform 2

Sequence length: 648 aa · 73052 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.