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ATM Rabbit mAb

58647

ATM Rabbit mAb

ATM Rabbit mAb (catalogue number 58647) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF FC, reactive with Human samples. It targets Serine-protein kinase ATM (ATM): Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human
Applications
WB IHC ICC/IF FC
UniProt ID
Q13315
Gene
ATM
Target organism
Homo sapiens
Catalogue number
58647
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: Serine-protein kinase ATM (ATM) · Homo sapiens

Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism.

Subcellular location: Nucleus; Cytoplasmic vesicle; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Peroxisome matrix

Tissue specificity: Found in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain, heart, spleen, thymus, testis, ovary, small intestine, colon and leukocytes

Sequence length: 3056 aa · 350687 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.