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EGFR (ErbB 1) Rabbit mAb

58589

EGFR (ErbB 1) Rabbit mAb

EGFR (ErbB 1) Rabbit mAb (catalogue number 58589) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB IHC ICC/IF IP FC, reactive with Human Mouse Rat samples. It targets Epidermal growth factor receptor (EGFR): Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

KDKO Validated Recombinant Monoclonal AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IHC ICC/IF IP FC
UniProt ID
P00533
Gene
EGFR
Target organism
Homo sapiens
Catalogue number
58589
Brand
LABO Scientific
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.

Target background

Target: Epidermal growth factor receptor (EGFR) · Homo sapiens

Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades.

Subcellular location: Cell membrane; Endoplasmic reticulum membrane; Golgi apparatus membrane; Nucleus membrane; Endosome; Endosome membrane; Nucleus

Tissue specificity: Ubiquitously expressed. Isoform 2 is also expressed in ovarian cancers

Sequence length: 1210 aa · 134277 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at +4˚C short term. Store at -20˚C long term. Avoid freeze / thaw cycle.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.