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Caspase 11 Rabbit mAb

57234

Caspase 11 Rabbit mAb

Caspase 11 Rabbit mAb (catalogue number 57234) is a rabbit-derived primary antibody validated for WB IP, reactive with Human, Mouse, Rat samples. It targets Caspase-4 (Casp4): Inflammatory caspase that acts as the effector of the non-canonical inflammasome by mediating lipopolysaccharide (LPS)-induced pyroptosis. Supplied as 100ul at ₪1,627.49; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
WB IP
UniProt ID
P70343
Gene
Casp4
Target organism
Mus musculus
Catalogue number
57234
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Caspase-4 (Casp4) · Mus musculus

Inflammatory caspase that acts as the effector of the non-canonical inflammasome by mediating lipopolysaccharide (LPS)-induced pyroptosis. Also indirectly activates the NLRP3 and NLRP6 inflammasomes. Acts as a thiol protease that cleaves a tetrapeptide after an Asp residue at position P1: catalyzes cleavage of CGAS and GSDMD. In contrast to its human ortholog, does not cleave IL18.

Subcellular location: Cytoplasm, cytosol; Cytoplasm; Endoplasmic reticulum membrane; Mitochondrion; Inflammasome; Secreted

Tissue specificity: Widely expressed, including in thymus, lung and spleen (at protein level). Very low levels, if any, in the brain

Sequence length: 373 aa · 42742 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.