56684
FE65 Rabbit mAb
FE65 Rabbit mAb (catalogue number 56684) is a recombinant rabbit-derived kdko validated recombinant monoclonal antibody validated for WB IHC ICC/IF, reactive with Human samples. It targets Amyloid beta precursor protein binding family B member 1 (APBB1): Transcription coregulator that can have both coactivator and corepressor functions. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human
- Applications
- WB IHC ICC/IF
- UniProt ID
- O00213
- Gene
- APBB1
- Target organism
- Homo sapiens
- Catalogue number
- 56684
- Brand
- LABO Scientific
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
Target background
Target: Amyloid beta precursor protein binding family B member 1 (APBB1) · Homo sapiens
Transcription coregulator that can have both coactivator and corepressor functions. Adapter protein that forms a transcriptionally active complex with the gamma-secretase-derived amyloid precursor protein (APP) intracellular domain. Plays a central role in the response to DNA damage by translocating to the nucleus and inducing apoptosis. May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), recruiting other pro-apoptosis factors such as MAPK8/JNK1.
Subcellular location: Cell membrane; Cytoplasm; Nucleus; Cell projection, growth cone; Nucleus speckle
Tissue specificity: Highly expressed in brain; strongly reduced in post-mortem elderly subjects with Alzheimer disease
Sequence length: 710 aa · 77244 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il