Loading...
NEK6 Rabbit mAb

56581

NEK6 Rabbit mAb

NEK6 Rabbit mAb (catalogue number 56581) is a recombinant rabbit-derived primary antibody validated for WB IP, reactive with Human Mouse Rat samples. It targets Serine/threonine-protein kinase Nek6 (NEK6): Protein kinase which plays an important role in mitotic cell cycle progression. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IP
UniProt ID
Q9HC98
Gene
NEK6
Target organism
Homo sapiens
Catalogue number
56581
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: Serine/threonine-protein kinase Nek6 (NEK6) · Homo sapiens

Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIRSR, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

Subcellular location: Cytoplasm; Nucleus; Nucleus speckle; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Cytoplasm, cytoskeleton, spindle pole

Tissue specificity: Ubiquitous, with highest expression in heart and skeletal muscle

Sequence length: 313 aa · 35714 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.