Loading...
NPC1L1 Rabbit mAb

56507

NPC1L1 Rabbit mAb

NPC1L1 Rabbit mAb (catalogue number 56507) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets NPC1-like intracellular cholesterol transporter 1 (NPC1L1): Plays a major role in cholesterol homeostasis. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
Q9UHC9
Gene
NPC1L1
Target organism
Homo sapiens
Catalogue number
56507
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: NPC1-like intracellular cholesterol transporter 1 (NPC1L1) · Homo sapiens

Plays a major role in cholesterol homeostasis. Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia. May have a function in the transport of multiple lipids and their homeostasis, thereby influencing lipid metabolism regulation. May be involved in caveolin trafficking from the plasma membrane.

Subcellular location: Apical cell membrane; Cell membrane; Cytoplasmic vesicle membrane

Tissue specificity: Widely expressed. Expressed in liver. Also expressed in small intestine, pancreas, kidney, lung, pancreas, spleen, heart, gall bladder, brain, testis, stomach and muscle

Sequence length: 1359 aa · 148728 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.