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RYBP Rabbit mAb

56453

RYBP Rabbit mAb

RYBP Rabbit mAb (catalogue number 56453) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF IP FC, reactive with Human Mouse Rat samples. It targets RING1 and YY1-binding protein (RYBP): Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human Mouse Rat
Applications
WB IHC ICC/IF IP FC
UniProt ID
Q8N488
Gene
RYBP
Target organism
Homo sapiens
Catalogue number
56453
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: RING1 and YY1-binding protein (RYBP) · Homo sapiens

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females.

Subcellular location: Nucleus; Cytoplasm; Nucleus, nucleoplasm

Tissue specificity: Down-regulated in breast cancer tissues and in several breast cancer cell lines (at protein level). Widely expressed with highest levels in lymphoid tissues and placenta

Sequence length: 228 aa · 24822 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.