56301
LYRIC Rabbit mAb
LYRIC Rabbit mAb (catalogue number 56301) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF, reactive with Human Mouse Rat samples. It targets Protein LYRIC (MTDH): Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Applications
- WB IHC ICC/IF
- UniProt ID
- Q86UE4
- Gene
- MTDH
- Target organism
- Homo sapiens
- Catalogue number
- 56301
- Brand
- LABO Scientific
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
Target background
Target: Protein LYRIC (MTDH) · Homo sapiens
Down-regulates SLC1A2/EAAT2 promoter activity when expressed ectopically. Activates the nuclear factor kappa-B (NF-kappa-B) transcription factor. Promotes anchorage-independent growth of immortalized melanocytes and astrocytes which is a key component in tumor cell expansion. Promotes lung metastasis and also has an effect on bone and brain metastasis, possibly by enhancing the seeding of tumor cells to the target organ endothelium. Induces chemoresistance
Subcellular location: Endoplasmic reticulum membrane; Nucleus membrane; Cell junction, tight junction; Nucleus, nucleolus; Cytoplasm, perinuclear region
Tissue specificity: Widely expressed with highest levels in muscle-dominating organs such as skeletal muscle, heart, tongue and small intestine and in endocrine glands such as thyroid and adrenal gland. Overexpressed in various cancers including breast, brain, prostate, melanoma and glioblastoma multiforme
Sequence length: 582 aa · 63837 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il