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RAP80 Rabbit mAb

56276

RAP80 Rabbit mAb

RAP80 Rabbit mAb (catalogue number 56276) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF, reactive with Human samples. It targets BRCA1-A complex subunit RAP80 (UIMC1): Ubiquitin-binding protein. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human
Applications
WB IHC ICC/IF
UniProt ID
Q96RL1
Gene
UIMC1
Target organism
Homo sapiens
Catalogue number
56276
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: BRCA1-A complex subunit RAP80 (UIMC1) · Homo sapiens

Ubiquitin-binding protein. Specifically recognizes and binds 'Lys-63'-linked ubiquitin. Plays a central role in the BRCA1-A complex by specifically binding 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. Also weakly binds monoubiquitin but with much less affinity than 'Lys-63'-linked ubiquitin.

Subcellular location: Nucleus

Tissue specificity: Expressed in testis, ovary, thymus and heart. Expressed in germ cells of the testis

Sequence length: 719 aa · 79727 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.