
56159
PML Rabbit mAb
PML Rabbit mAb (catalogue number 56159) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF IP FC, reactive with Human Mouse Rat samples. It targets Protein PML (PML): Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Applications
- WB IHC ICC/IF IP FC
- UniProt ID
- P29590
- Gene
- PML
- Target organism
- Homo sapiens
- Catalogue number
- 56159
- Brand
- LABO Scientific
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
Target background
Target: Protein PML (PML) · Homo sapiens
Functions via its association with PML-nuclear bodies (PML-NBs) in a wide range of important cellular processes, including tumor suppression, transcriptional regulation, apoptosis, senescence, DNA damage response, and viral defense mechanisms. Acts as the scaffold of PML-NBs allowing other proteins to shuttle in and out, a process which is regulated by SUMO-mediated modifications and interactions. Inhibits EIF4E-mediated mRNA nuclear export by reducing EIF4E affinity for the 5' 7-methylguanosine (m7G) cap of target mRNAs.
Subcellular location: Nucleus; Nucleus, nucleoplasm; Cytoplasm; Nucleus, PML body; Nucleus, nucleolus; Endoplasmic reticulum membrane; Early endosome membrane
Sequence length: 882 aa · 97551 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il