56154
Rac1/2/3 Rabbit mAb
Rac1/2/3 Rabbit mAb (catalogue number 56154) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human Mouse Rat samples. It targets Ras-related C3 botulinum toxin substrate 1 (RAC1): Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Recombinant Rabbit
- Reactivity
- Human Mouse Rat
- Applications
- Western blot
- UniProt ID
- P63000
- Gene
- RAC1
- Target organism
- Homo sapiens
- Catalogue number
- 56154
- Brand
- LABO Scientific
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
Target background
Target: Ras-related C3 botulinum toxin substrate 1 (RAC1) · Homo sapiens
Plasma membrane-associated small GTPase which cycles between active GTP-bound and inactive GDP-bound states. In its active state, binds to a variety of effector proteins to regulate cellular responses such as secretory processes, phagocytosis of apoptotic cells, epithelial cell polarization, neurons adhesion, migration and differentiation, and growth-factor induced formation of membrane ruffles. Rac1 p21/rho GDI heterodimer is the active component of the cytosolic factor sigma 1, which is involved in stimulation of the NADPH oxidase activity in macrophages.
Subcellular location: Cell membrane; Melanosome; Cytoplasm; Cell projection, lamellipodium; Cell projection, dendrite; Synapse; Nucleus; Cell projection, ruffle membrane
Tissue specificity: Isoform B is predominantly identified in skin and epithelial tissues from the intestinal tract. Its expression is elevated in colorectal tumors at various stages of neoplastic progression, as compared to their respective adjacent tissues
Sequence length: 192 aa · 21450 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C. Avoid freeze/thaw cycles.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il