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HIF-1 alpha Rabbit mAb

56033

HIF-1 alpha Rabbit mAb

HIF-1 alpha Rabbit mAb (catalogue number 56033) is a recombinant rabbit-derived primary antibody validated for WB IHC ICC/IF IP FC, reactive with Human samples. It targets Hypoxia-inducible factor 1-alpha (HIF1A): Functions as a master transcriptional regulator of the adaptive response to hypoxia. Supplied in 2 pack sizes, from 50ul at ₪1,015.65 to 100ul at ₪1,382.75; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human
Applications
WB IHC ICC/IF IP FC
UniProt ID
Q16665
Gene
HIF1A
Target organism
Homo sapiens
Catalogue number
56033
Brand
LABO Scientific
Storage
Store at -20°C. Avoid freeze/thaw cycles.

Target background

Target: Hypoxia-inducible factor 1-alpha (HIF1A) · Homo sapiens

Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease.

Subcellular location: Cytoplasm; Nucleus; Nucleus speckle

Tissue specificity: Expressed in most tissues with highest levels in kidney and heart. Overexpressed in the majority of common human cancers and their metastases, due to the presence of intratumoral hypoxia and as a result of mutations in genes encoding oncoproteins and tumor suppressors.

Sequence length: 826 aa · 92670 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C. Avoid freeze/thaw cycles.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.