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FANCM Rabbit Polyclonal Antibody

55260

FANCM Rabbit Polyclonal Antibody

FANCM Rabbit Polyclonal Antibody (catalogue number 55260) is a rabbit-derived primary antibody validated for Western blot, Immunofluorescence, reactive with Human samples. It targets Fanconi anemia group M protein (FANCM): DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot Immunofluorescence
UniProt ID
Q8IYD8
Gene
FANCM
Target organism
Homo sapiens
Catalogue number
55260
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Fanconi anemia group M protein (FANCM) · Homo sapiens

DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork.

Subcellular location: Nucleus

Tissue specificity: Expressed in germ cells of fetal and adult ovaries. In fetal ovaries, it is present in oogonia but expression is stronger in pachytene stage oocytes. Expressed in oocytes arrested at the diplotene stage of prophase I during the last trimester of pregnancy and in adults. Expressed in the testis

Sequence length: 2048 aa · 232191 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.