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AKAP8 Rabbit Polyclonal Antibody

54738

AKAP8 Rabbit Polyclonal Antibody

AKAP8 Rabbit Polyclonal Antibody (catalogue number 54738) is a rabbit-derived primary antibody validated for Western blot, Immunofluorescence, reactive with Human, Mouse samples. It targets A-kinase anchor protein 8 (AKAP8): Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunofluorescence
UniProt ID
O43823
Gene
AKAP8
Target organism
Homo sapiens
Catalogue number
54738
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: A-kinase anchor protein 8 (AKAP8) · Homo sapiens

Anchoring protein that mediates the subcellular compartmentation of cAMP-dependent protein kinase (PKA type II). Acts as an anchor for a PKA-signaling complex onto mitotic chromosomes, which is required for maintenance of chromosomes in a condensed form throughout mitosis. Recruits condensin complex subunit NCAPD2 to chromosomes required for chromatin condensation; the function appears to be independent from PKA-anchoring. May help to deliver cyclin D/E to CDK4 to facilitate cell cycle progression. Required for cell cycle G2/M transition and histone deacetylation during mitosis.

Subcellular location: Nucleus; Nucleus matrix; Nucleus, nucleolus; Cytoplasm

Tissue specificity: Highly expressed in heart, liver, skeletal muscle, kidney and pancreas. Expressed in mature dendritic cells

Sequence length: 692 aa · 76108 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.