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JMJD1C Rabbit Polyclonal Antibody

54639

JMJD1C Rabbit Polyclonal Antibody

JMJD1C Rabbit Polyclonal Antibody (catalogue number 54639) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Human, Mouse, Rat samples. It targets Jumonji domain-containing protein 1C (JMJD1C): Demethylates lysine in proteins, such as STAT3 or MDC1. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot Immunohistochemistry
UniProt ID
Q15652
Gene
JMJD1C
Target organism
Homo sapiens
Catalogue number
54639
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Jumonji domain-containing protein 1C (JMJD1C) · Homo sapiens

Demethylates lysine in proteins, such as STAT3 or MDC1. Demethylates MDC1, thereby promoting MDC1-RNF8 interaction and facilitating RNF8-dependent MDC1 ubiquitination essential for double-strand break (DSB) repair. Demethylation of STAT3 at 'Lys-140' facilitates its interactions with the phosphatase PTPN6 and restrains STAT3 activation. It is uncertain whether JMJD1C removes methyl groups from histone proteins as the other JMJD1/KDM3 proteins do. Nevertheless, JMJD1C may act as a context-specific histone demethylase.

Subcellular location: Nucleus

Sequence length: 2540 aa · 284525 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.