
54421
SCRIB Rabbit Polyclonal Antibody
SCRIB Rabbit Polyclonal Antibody (catalogue number 54421) is a rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Protein scribble homolog (SCRIB): Scaffold protein involved in different aspects of polarized cell differentiation regulating epithelial and neuronal morphogenesis and T-cell polarization. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- Western blot
- UniProt ID
- Q14160
- Gene
- SCRIB
- Target organism
- Homo sapiens
- Catalogue number
- 54421
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Protein scribble homolog (SCRIB) · Homo sapiens
Scaffold protein involved in different aspects of polarized cell differentiation regulating epithelial and neuronal morphogenesis and T-cell polarization. Via its interaction with CRTAM, required for the late phase polarization of a subset of CD4+ T-cells, which in turn regulates TCR-mediated proliferation and IFNG and IL22 production. Plays a role in cell directional movement, cell orientation, cell sheet organization and Golgi complex polarization at the cell migration front. Promotes epithelial cell layer barrier function via maintaining cell-cell adhesion.
Subcellular location: Cell membrane; Cell junction; Cell junction, adherens junction; Cell projection, lamellipodium; Cytoplasm; Postsynapse; Presynapse
Tissue specificity: Expressed in kidney, skeletal muscles, liver, lung, breast, intestine, placenta and skin mainly in epithelial cells (at protein level)
Sequence length: 1655 aa · 177724 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il