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HSD17B7 Rabbit Polyclonal Antibody

54384

HSD17B7 Rabbit Polyclonal Antibody

HSD17B7 Rabbit Polyclonal Antibody (catalogue number 54384) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Human, Mouse samples. It targets 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (HSD17B7): Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunohistochemistry
UniProt ID
P56937
Gene
HSD17B7
Target organism
Homo sapiens
Catalogue number
54384
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: 3-keto-steroid reductase/17-beta-hydroxysteroid dehydrogenase 7 (HSD17B7) · Homo sapiens

Bifunctional enzyme involved in steroid-hormone metabolism and cholesterol biosynthesis. Catalyzes the NADP(H)-dependent reduction of estrogens and androgens and regulates the biological potency of these steroids. Converts estrone (E1) to a more potent estrogen, 17beta-estradiol (E2). Converts dihydrotestosterone (DHT) to its inactive form 5a-androstane-3b,17b-diol. Converts moderately progesterone to 3beta-hydroxypregn-4-ene-20-one, leading to its inactivation. Additionally, participates in the post-squalene cholesterol biosynthesis, as a 3-ketosteroid reductase

Subcellular location: Endoplasmic reticulum membrane

Tissue specificity: Highly expressed in adrenal gland, liver, lung and thymus. Expressed in breast, ovaries, pituitary gland, pregnant uterus, prostate, kidney, lymph node, small intestine, spinal cord and trachea. Weakly expressed in all other tissues tested

Sequence length: 341 aa · 38206 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.