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GDF5 Rabbit Polyclonal Antibody

53517

GDF5 Rabbit Polyclonal Antibody

GDF5 Rabbit Polyclonal Antibody (catalogue number 53517) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, reactive with Mouse, Rat samples. It targets Growth/differentiation factor 5 (GDF5): Growth factor involved in bone and cartilage formation. Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Mouse, Rat
Applications
Western blot Immunohistochemistry
UniProt ID
P43026
Gene
GDF5
Target organism
Homo sapiens
Catalogue number
53517
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Growth/differentiation factor 5 (GDF5) · Homo sapiens

Growth factor involved in bone and cartilage formation. During cartilage development regulates differentiation of chondrogenic tissue through two pathways. Firstly, positively regulates differentiation of chondrogenic tissue through its binding of high affinity with BMPR1B and of less affinity with BMPR1A, leading to induction of SMAD1-SMAD5-SMAD8 complex phosphorylation and then SMAD protein signaling transduction. Secondly, negatively regulates chondrogenic differentiation through its interaction with NOG. Required to prevent excessive muscle loss upon denervation.

Subcellular location: Secreted; Cell membrane

Tissue specificity: Predominantly expressed in long bones during embryonic development. Expressed in monocytes (at protein level)

Sequence length: 501 aa · 55395 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.