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ITPR3 Rabbit Polyclonal Antibody

53440

ITPR3 Rabbit Polyclonal Antibody

ITPR3 Rabbit Polyclonal Antibody (catalogue number 53440) is a rabbit-derived primary antibody validated for Western blot, Immunofluorescence, reactive with Human, Mouse samples. It targets Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 (ITPR3): Inositol 1,4,5-trisphosphate-gated calcium channel that, upon 1D-myo-inositol 1,4,5-trisphosphate binding, transports calcium from the endoplasmic reticulum lumen to cytoplasm, thus releasing the intracellular calcium and therefore participates in cellular ca… Supplied in 2 pack sizes, from 50ul at ₪1,260.38 to 100ul at ₪1,790.64; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunofluorescence
UniProt ID
Q14573
Gene
ITPR3
Target organism
Homo sapiens
Catalogue number
53440
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3 (ITPR3) · Homo sapiens

Inositol 1,4,5-trisphosphate-gated calcium channel that, upon 1D-myo-inositol 1,4,5-trisphosphate binding, transports calcium from the endoplasmic reticulum lumen to cytoplasm, thus releasing the intracellular calcium and therefore participates in cellular calcium ion homeostasis. 1D-myo-inositol 1,4,5-trisphosphate binds to the ligand-free channel without altering its global conformation, yielding the low-energy resting state, then progresses through resting-to preactivated transitions to the higher energy preactivated state, which increases affinity for calcium, promoting binding of the low…

Subcellular location: Endoplasmic reticulum membrane; Cytoplasmic vesicle, secretory vesicle membrane

Tissue specificity: Expressed in intestinal crypt and villus epithelial cells

Sequence length: 2671 aa · 304106 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.