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CREB Regulated Transcription Coactivator 2 Rabbit mAb

52873

CREB Regulated Transcription Coactivator 2 Rabbit mAb

CREB Regulated Transcription Coactivator 2 Rabbit mAb (catalogue number 52873) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets CREB-regulated transcription coactivator 2 (CRTC2): Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q53ET0
Gene
CRTC2
Target organism
Homo sapiens
Catalogue number
52873
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: CREB-regulated transcription coactivator 2 (CRTC2) · Homo sapiens

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. Regulates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells.

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Most abundantly expressed in the thymus. Present in both B and T-lymphocytes. Highly expressed in HEK293T cells and in insulinomas. High levels also in spleen, ovary, muscle and lung, with highest levels in muscle.

Sequence length: 693 aa · 73302 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.