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Rab7B Rabbit mAb

52539

Rab7B Rabbit mAb

Rab7B Rabbit mAb (catalogue number 52539) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse samples. It targets Ras-related protein Rab-7b (RAB7B): Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human, Mouse
Applications
Western blot
UniProt ID
Q96AH8
Gene
RAB7B
Target organism
Homo sapiens
Catalogue number
52539
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Ras-related protein Rab-7b (RAB7B) · Homo sapiens

Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway

Subcellular location: Late endosome; Lysosome; Golgi apparatus; Golgi apparatus, trans-Golgi network; Cytoplasmic vesicle, phagosome; Cytoplasmic vesicle, phagosome membrane

Tissue specificity: Expressed in heart, placenta, lung, skeletal muscle and peripheral blood leukocyte

Sequence length: 199 aa · 22511 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.