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Metabotropic Glutamate Receptor 2 Rabbit mAb

52415

Metabotropic Glutamate Receptor 2 Rabbit mAb

Metabotropic Glutamate Receptor 2 Rabbit mAb (catalogue number 52415) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human, Mouse, Rat samples. It targets Metabotropic glutamate receptor 2 (GRM2): Dimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot
UniProt ID
Q14416
Gene
GRM2
Target organism
Homo sapiens
Catalogue number
52415
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Metabotropic glutamate receptor 2 (GRM2) · Homo sapiens

Dimeric G protein-coupled receptor which is activated by the excitatory neurotransmitter L-glutamate. Plays critical roles in modulating synaptic transmission and neuronal excitability. Upon activation by glutamate, inhibits presynaptic calcium channels, reducing further glutamate release and dampening excitatory signaling. Mechanistically, ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase.

Subcellular location: Cell membrane; Synapse; Cell projection, dendrite

Tissue specificity: Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain

Sequence length: 872 aa · 95568 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.