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DOCK8 Rabbit mAb

52258

DOCK8 Rabbit mAb

DOCK8 Rabbit mAb (catalogue number 52258) is a recombinant rabbit-derived primary antibody validated for Western blot, reactive with Human samples. It targets Dedicator of cytokinesis protein 8 (DOCK8): Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRecombinant Rabbit
Host / source
Recombinant Rabbit
Reactivity
Human
Applications
Western blot
UniProt ID
Q8NF50
Gene
DOCK8
Target organism
Homo sapiens
Catalogue number
52258
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Dedicator of cytokinesis protein 8 (DOCK8) · Homo sapiens

Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane.

Subcellular location: Cytoplasm; Cell membrane; Cell projection, lamellipodium membrane

Tissue specificity: Expressed in peripheral blood mononuclear cells (PBMCs)

Sequence length: 2099 aa · 238529 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.