Loading...
p54nrb Antibody

49948

p54nrb Antibody

p54nrb Antibody (catalogue number 49948) is a rabbit-derived primary antibody validated for Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, reactive with Human, Mouse, Rat samples. It targets Non-POU domain-containing octamer-binding protein (NONO): DNA- and RNA binding protein, involved in several nuclear processes. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot Immunocytochemistry Immunofluorescence Immunohistochemistry
UniProt ID
Q15233
Gene
NONO
Target organism
Homo sapiens
Catalogue number
49948
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Non-POU domain-containing octamer-binding protein (NONO) · Homo sapiens

DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. Together with PSPC1, required for the formation of nuclear paraspeckles. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs.

Subcellular location: Nucleus; Nucleus, nucleolus; Nucleus speckle; Chromosome

Tissue specificity: Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Also found in a number of breast tumor cell lines

Sequence length: 471 aa · 54232 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.