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CKR-2 Polyclonal Antibody

49866

CKR-2 Polyclonal Antibody

CKR-2 Polyclonal Antibody (catalogue number 49866) is a rabbit-derived primary antibody validated for Western blot, Immunofluorescence, ELISA, reactive with Mouse, Rat samples. It targets C-C chemokine receptor type 2 (CCR2): Key functional receptor for CCL2 but can also bind CCL7, and CCL12. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Mouse, Rat
Applications
Western blot Immunofluorescence ELISA
UniProt ID
P41597
Gene
CCR2
Target organism
Homo sapiens
Catalogue number
49866
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: C-C chemokine receptor type 2 (CCR2) · Homo sapiens

Key functional receptor for CCL2 but can also bind CCL7, and CCL12. Also transduces signaling mediated by CCL13. Its binding with CCL2 on monocytes and macrophages mediates chemotaxis and migration induction through the activation of the PI3K cascade, the small G protein Rac and lamellipodium protrusion. Also acts as a receptor for the beta-defensin DEFB106A/DEFB106B. Regulates the expression of T-cell inflammatory cytokines and T-cell differentiation, promoting the differentiation of T-cells into T-helper 17 cells (Th17) during inflammation.

Subcellular location: Cell membrane

Tissue specificity: Expressed by monocytes and IL2-activated NK cells. Abundantly expressed on CD14+/CD16- monocytes and weakly on CD14+/CD16+ monocytes, type 2 dendritic cells (DCs) and plasmacytoid DCs (at protein level)

Sequence length: 374 aa · 41915 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.