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DSG1 Antibody

49862

DSG1 Antibody

DSG1 Antibody (catalogue number 49862) is a rabbit-derived primary antibody validated for Western blot, Immunocytochemistry, Immunofluorescence, IHC-P, reactive with Human, Mouse, Rat, Zebrafish samples. It targets Desmoglein-1 (DSG1): A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Applications
Western blot Immunocytochemistry Immunofluorescence IHC-P
UniProt ID
Q02413
Gene
DSG1
Target organism
Homo sapiens
Catalogue number
49862
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Desmoglein-1 (DSG1) · Homo sapiens

A component of desmosome cell-cell junctions which are required for positive regulation of cellular adhesion. Promotes differentiation of keratinocytes via interaction with ERBIN. Reduces activation of RAS/ERK signaling pathways in keratinocytes via promoting ERBIN localization to the cell membrane and its interaction with SHOC2, this competitively reduces the formation of RAS-SHOC2 ERK-activating complexes. Mediates the interaction between the desmosome and COP9 signalosome complex (CSN) protein complex.

Subcellular location: Cell membrane; Cell junction, desmosome; Cytoplasm; Nucleus

Tissue specificity: Expressed in all suprabasal layers of the epidermis, with the highest expression seen in the granular layer (at protein level). Expressed in the suprabasal esophageal epithelium (at protein level)

Sequence length: 1049 aa · 113748 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.