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Nesprin 1 Antibody

49810

Nesprin 1 Antibody

Nesprin 1 Antibody (catalogue number 49810) is a rabbit-derived primary antibody validated for Western blot, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Flow cytometry, reactive with Human, Mouse, Rat samples. It targets Nesprin-1 (SYNE1): Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot Immunocytochemistry Immunofluorescence Immunohistochemistry Flow cytometry
UniProt ID
Q8NF91
Gene
SYNE1
Target organism
Homo sapiens
Catalogue number
49810
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Nesprin-1 (SYNE1) · Homo sapiens

Multi-isomeric modular protein which forms a linking network between organelles and the actin cytoskeleton to maintain the subcellular spatial organization. As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning.

Subcellular location: Nucleus outer membrane; Nucleus; Nucleus envelope; Cytoplasm, cytoskeleton; Cytoplasm, myofibril, sarcomere

Tissue specificity: Expressed in HeLa, A431, A172 and HaCaT cells (at protein level). Widely expressed. Highly expressed in skeletal and smooth muscles, heart, spleen, peripheral blood leukocytes, pancreas, cerebellum, stomach, kidney and placenta.

Sequence length: 8797 aa · 1011086 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.