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Epac1 Antibody

49669

Epac1 Antibody

Epac1 Antibody (catalogue number 49669) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, Immunoprecipitation, ICC/IF, reactive with Human, Mouse samples. It targets Rap guanine nucleotide exchange factor 3 (RAPGEF3): Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunohistochemistry Immunoprecipitation ICC/IF
UniProt ID
O95398
Gene
RAPGEF3
Target organism
Homo sapiens
Catalogue number
49669
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Rap guanine nucleotide exchange factor 3 (RAPGEF3) · Homo sapiens

Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. Through simultaneous binding of PDE3B to RAPGEF3 and PIK3R6 is assembled in a signaling complex in which it activates the PI3K gamma complex and which is involved in angiogenesis. Plays a role in the modulation of the cAMP-induced dynamic control of endothelial barrier function through a pathway that is independent on Rho-mediated signaling. Required for the actin rearrangement at cell-cell junctions, such as stress fibers and junctional actin

Subcellular location: Endomembrane system

Tissue specificity: Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney

Sequence length: 923 aa · 103751 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.