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Calcineurin A Antibody

49514

Calcineurin A Antibody

Calcineurin A Antibody (catalogue number 49514) is a rabbit-derived primary antibody validated for Western blot, Flow cytometry, reactive with Human, Mouse, Rat samples. It targets Protein phosphatase 3 catalytic subunit alpha (PPP3CA): Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat
Applications
Western blot Flow cytometry
UniProt ID
Q08209
Gene
PPP3CA
Target organism
Homo sapiens
Catalogue number
49514
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Protein phosphatase 3 catalytic subunit alpha (PPP3CA) · Homo sapiens

Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals. Many of the substrates contain a PxIxIT motif and/or a LxVP motif. In response to increased Ca(2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation. In response to increased Ca(2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion.

Subcellular location: Cytoplasm; Cell membrane; Cell membrane, sarcolemma; Cytoplasm, myofibril, sarcomere, Z line; Cell projection, dendritic spine

Tissue specificity: Expressed in keratinocytes (at protein level). Expressed in lymphoblasts (at protein level)

Sequence length: 521 aa · 58688 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.