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TDP43 Antibody

49487

TDP43 Antibody

TDP43 Antibody (catalogue number 49487) is a rabbit-derived primary antibody validated for Western blot, Immunoprecipitation, ICC/IF, Immunohistochemistry, Flow cytometry, reactive with Human, Mouse, Rat, Zebrafish samples. It targets TAR DNA-binding protein 43 (TARDBP): RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse, Rat, Zebrafish
Applications
Western blot Immunoprecipitation ICC/IF Immunohistochemistry Flow cytometry
UniProt ID
Q13148
Gene
TARDBP
Target organism
Homo sapiens
Catalogue number
49487
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: TAR DNA-binding protein 43 (TARDBP) · Homo sapiens

RNA-binding protein that is involved in various steps of RNA biogenesis and processing. Preferentially binds, via its two RNA recognition motifs RRM1 and RRM2, to GU-repeats on RNA molecules predominantly localized within long introns and in the 3'UTR of mRNAs. In turn, regulates the splicing of many non-coding and protein-coding RNAs including proteins involved in neuronal survival, as well as mRNAs that encode proteins relevant for neurodegenerative diseases. Plays a role in maintaining mitochondrial homeostasis by regulating the processing of mitochondrial transcripts.

Subcellular location: Nucleus; Cytoplasm; Cytoplasm, Stress granule; Mitochondrion

Tissue specificity: Ubiquitously expressed. In particular, expression is high in pancreas, placenta, lung, genital tract and spleen

Sequence length: 414 aa · 44740 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.