
49268
CD3D Antibody
CD3D Antibody (catalogue number 49268) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, ICC/IF, Immunoprecipitation, Flow cytometry, reactive with Human samples. It targets T-cell surface glycoprotein CD3 delta chain (CD3D): Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- Western blot Immunohistochemistry ICC/IF Immunoprecipitation Flow cytometry
- UniProt ID
- P04234
- Gene
- CD3D
- Target organism
- Homo sapiens
- Catalogue number
- 49268
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: T-cell surface glycoprotein CD3 delta chain (CD3D) · Homo sapiens
Part of the TCR-CD3 complex present on T-lymphocyte cell surface that plays an essential role in adaptive immune response. When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD247/CD3Z. All CD3 chains contain immunoreceptor tyrosine-based activation motifs (ITAMs) in their cytoplasmic domain. Upon TCR engagement, these motifs become phosphorylated by Src family protein tyrosine kinases LCK and FYN, resulting in the activation of downstream signaling pathways.
Subcellular location: Cell membrane
Tissue specificity: CD3D is mostly present on T-lymphocytes with its TCR-CD3 partners. Present also in fetal NK-cells
Sequence length: 171 aa · 18930 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il