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p14ARF Polyclonal Antibody

49256

p14ARF Polyclonal Antibody

p14ARF Polyclonal Antibody (catalogue number 49256) is a rabbit-derived primary antibody validated for Western blot, Immunohistochemistry, Immunofluorescence, ELISA, reactive with Human, Rat, Mouse samples. It targets Tumor suppressor ARF (CDKN2A): Capable of inducing cell cycle arrest in G1 and G2 phases. Supplied in 2 pack sizes, from 50ul at ₪893.28 to 100ul at ₪1,301.17; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Rat, Mouse
Applications
Western blot Immunohistochemistry Immunofluorescence ELISA
UniProt ID
Q8N726
Gene
CDKN2A
Target organism
Homo sapiens
Catalogue number
49256
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Tumor suppressor ARF (CDKN2A) · Homo sapiens

Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Binds to MDM2 and blocks its nucleocytoplasmic shuttling by sequestering it in the nucleolus. This inhibits the oncogenic action of MDM2 by blocking MDM2-induced degradation of p53 and enhancing p53-dependent transactivation and apoptosis. Also induces G2 arrest and apoptosis in a p53-independent manner by preventing the activation of cyclin B1/CDC2 complexes. Binds to BCL6 and down-regulates BCL6-induced transcriptional repression.

Subcellular location: Nucleus, nucleolus; Nucleus, nucleoplasm

Sequence length: 132 aa · 13903 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.