
48751
PI 3 Kinase catalytic subunit alpha Antibody
PI 3 Kinase catalytic subunit alpha Antibody (catalogue number 48751) is a rabbit-derived primary antibody validated for Western blot, ICC/IF, Immunoprecipitation, reactive with Human, Mouse samples. It targets Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA): Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪2,035.38; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human, Mouse
- Applications
- Western blot ICC/IF Immunoprecipitation
- UniProt ID
- P42336
- Gene
- PIK3CA
- Target organism
- Homo sapiens
- Catalogue number
- 48751
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) · Homo sapiens
Phosphoinositide-3-kinase (PI3K) phosphorylates phosphatidylinositol (PI) and its phosphorylated derivatives at position 3 of the inositol ring to produce 3-phosphoinositides. Uses ATP and PtdIns(4,5)P2 (phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5-trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Participates in cellular signaling in response to various growth factors.
Sequence length: 1068 aa · 124284 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il