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BubR1 Antibody

48538

BubR1 Antibody

BubR1 Antibody (catalogue number 48538) is a rabbit-derived primary antibody validated for Western blot, Immunocytochemistry, Immunohistochemistry, Flow cytometry, reactive with Human samples. It targets Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B): Component of the mitotic checkpoint complex (MCC), which inhibits APC/C and delays chromosome segregation until all chromosomes are properly attached to the mitotic spindle. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human
Applications
Western blot Immunocytochemistry Immunohistochemistry Flow cytometry
UniProt ID
O60566
Gene
BUB1B
Target organism
Homo sapiens
Catalogue number
48538
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) · Homo sapiens

Component of the mitotic checkpoint complex (MCC), which inhibits APC/C and delays chromosome segregation until all chromosomes are properly attached to the mitotic spindle. The MCC, which consists of CDC20, MAD2L1/MAD2, BUB1B/BUBR1 and BUB3, is a key player of the spindle assembly checkpoint. The MCC-bound APC/C complex is inactive and this delays the metaphase/anaphase transition.

Subcellular location: Cytoplasm; Nucleus; Chromosome, centromere, kinetochore; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome

Tissue specificity: Highly expressed in thymus followed by spleen. Preferentially expressed in tissues with a high mitotic index

Sequence length: 1050 aa · 119545 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.