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THAP1 Antibody

48420

THAP1 Antibody

THAP1 Antibody (catalogue number 48420) is a mouse-derived primary antibody validated for Western blot, Immunocytochemistry, Flow cytometry, reactive with Human samples. It targets THAP domain-containing protein 1 (THAP1): DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Western blot Immunocytochemistry Flow cytometry
UniProt ID
Q9NVV9
Gene
THAP1
Target organism
Homo sapiens
Catalogue number
48420
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: THAP domain-containing protein 1 (THAP1) · Homo sapiens

DNA-binding transcription regulator that regulates endothelial cell proliferation and G1/S cell-cycle progression. Specifically binds the 5'-[AT]NTNN[GT]GGCA[AGT]-3' core DNA sequence and acts by modulating expression of pRB-E2F cell-cycle target genes, including RRM1. Component of a THAP1/THAP3-HCFC1-OGT complex that is required for the regulation of the transcriptional activity of RRM1. May also have pro-apoptotic activity by potentiating both serum-withdrawal and TNF-induced apoptosis

Subcellular location: Nucleus, nucleoplasm; Nucleus, PML body

Tissue specificity: Highly expressed in heart, skeletal muscle, kidney and liver. Weaker expression in brain and placenta

Sequence length: 213 aa · 24944 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.