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SK2 Antibody

48406

SK2 Antibody

SK2 Antibody (catalogue number 48406) is a mouse-derived primary antibody validated for Immunocytochemistry, Immunohistochemistry, Flow cytometry, reactive with Human samples. It targets Sphingosine kinase 2 (SPHK2): Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Immunocytochemistry Immunohistochemistry Flow cytometry
UniProt ID
Q9NRA0
Gene
SPHK2
Target organism
Homo sapiens
Catalogue number
48406
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: Sphingosine kinase 2 (SPHK2) · Homo sapiens

Catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions. Also acts on D-erythro-dihydrosphingosine, D-erythro-sphingosine and L-threo-dihydrosphingosine. Binds phosphoinositides. In contrast to prosurvival SPHK1, has a positive effect on intracellular ceramide levels, inhibits cells growth and enhances apoptosis. In mitochondria, is important for cytochrome-c oxidase assembly and mitochondrial respiration.

Subcellular location: Cytoplasm; Nucleus; Endoplasmic reticulum; Mitochondrion inner membrane

Tissue specificity: Mainly expressed in adult kidney, liver, and brain. Expressed in cerebral cortex and hippocampus (at protein level). Isoform 1 is the predominant form expressed in most tissues

Sequence length: 654 aa · 69217 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.