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HLA E Antibody

48304

HLA E Antibody

HLA E Antibody (catalogue number 48304) is a mouse-derived primary antibody validated for Western blot, Immunoprecipitation, FCM, reactive with Human samples. It targets HLA class I histocompatibility antigen, alpha chain E (HLA-E): Non-classical major histocompatibility class Ib molecule involved in immune self-nonself discrimination. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostMouse
Host / source
Mouse
Reactivity
Human
Applications
Western blot Immunoprecipitation FCM
UniProt ID
P13747
Gene
HLA-E
Target organism
Homo sapiens
Catalogue number
48304
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: HLA class I histocompatibility antigen, alpha chain E (HLA-E) · Homo sapiens

Non-classical major histocompatibility class Ib molecule involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglobulin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molecules (VL9 peptides - VMAPRT[V/L][L/V/I/F]L). Peptide-bound HLA-E-B2M heterotrimeric complex primarily functions as a ligand for natural killer (NK) cell inhibitory receptor KLRD1-KLRC1, enabling NK cells to monitor the expression of other MHC class I molecules in healthy cells and to tolerate self.

Subcellular location: Cell membrane; Golgi apparatus membrane

Tissue specificity: Expressed in secretory endometrial cells during pregnancy (at protein level). The expression in nonlymphoid tissues is restricted to endothelial cells from all types of vessels, including arteries, veins, capillaries, and lymphatics (at protein level).

Sequence length: 358 aa · 40058 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.