
48265
Sir2/SIRT1 Antibody
Sir2/SIRT1 Antibody (catalogue number 48265) is a rabbit-derived primary antibody validated for Western blot, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, reactive with Human samples. It targets NAD-dependent protein deacetylase sirtuin-1 (SIRT1): NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and aut… Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.
- Host / source
- Rabbit
- Reactivity
- Human
- Applications
- Western blot Immunocytochemistry Immunohistochemistry Immunoprecipitation
- UniProt ID
- Q96EB6
- Gene
- SIRT1
- Target organism
- Homo sapiens
- Catalogue number
- 48265
- Brand
- LABO Scientific
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Target background
Target: NAD-dependent protein deacetylase sirtuin-1 (SIRT1) · Homo sapiens
NAD-dependent protein deacetylase that links transcriptional regulation directly to intracellular energetics and participates in the coordination of several separated cellular functions such as cell cycle, response to DNA damage, metabolism, apoptosis and autophagy. Can modulate chromatin function through deacetylation of histones and can promote alterations in the methylation of histones and DNA, leading to transcriptional repression. Deacetylates a broad range of transcription factors and coregulators, thereby regulating target gene expression positively and negatively.
Subcellular location: Nucleus, PML body; Cytoplasm; Nucleus
Tissue specificity: Widely expressed
Sequence length: 747 aa · 81681 Da
Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Storage
- Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il