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MRKN2 Antibody

48180

MRKN2 Antibody

MRKN2 Antibody (catalogue number 48180) is a rabbit-derived primary antibody validated for Western blot, Immunocytochemistry, Immunohistochemistry, reactive with Human, Mouse samples. It targets E3 ubiquitin-protein ligase makorin-2 (MKRN2): E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Supplied in 2 pack sizes, from 50ul at ₪1,219.60 to 100ul at ₪1,749.85; the final price is confirmed on your quote and the lot certificate of analysis ships with the order.

Primary AntibodyHostRabbit
Host / source
Rabbit
Reactivity
Human, Mouse
Applications
Western blot Immunocytochemistry Immunohistochemistry
UniProt ID
Q9H000
Gene
MKRN2
Target organism
Homo sapiens
Catalogue number
48180
Brand
LABO Scientific
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.

Target background

Target: E3 ubiquitin-protein ligase makorin-2 (MKRN2) · Homo sapiens

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Promotes the polyubiquitination and proteasome-dependent degradation of RELA/p65, thereby suppressing RELA-mediated NF-kappaB transactivation and negatively regulating inflammatory responses. Plays a role in the regulation of spermiation and in male fertility

Subcellular location: Cytoplasm; Nucleus

Tissue specificity: Expressed in sperm, with significantly reduced expression in sperm of patients with oligoasthenoteratozoospermia (at protein level). Widely expressed with expression in testis, ovary, small intestine, colon, peripheral blood leukocytes, fetal liver, bone marrow, thymus, lymph node and spleen

Sequence length: 416 aa · 46940 Da

Protein background from UniProtKB, licensed under CC BY 4.0. Describes the target antigen, not this product.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Storage
Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.